2016.11-2019.06加入武汉大学药学院周海兵课题组,完成本科毕业设计课题并且攻读硕士1.选择性雌激素受体调节剂的设计、合成及活性研究
2.雌激素受体靶向性荧光探针的设计、合成及生物活性研究
2019.06-至今加入武汉大学药学院将中兴课题组,攻读博士学位
1.氟-19磁共振可视化药物载体的设计、合成及其在抗肿瘤研究中的应用
2.通过叠氮化合物的还原二聚化合成支单分散低聚乙二醇并应用于19F MRI可追踪生物材料3. PEG类化合物的合成与应用
[1] Jing Zhang, Yuan Yuan, Yu Li, et al. Synthesis of Branched Monodisperse Oligoethylene Glycols and 19MRI-Traceable Biomaterials through Reductive Dimerization of Azides. The Journa/ of Organic Chemistry.2020, 85, 6778.
[2] Xueke Peng, Zhiye Hu, Jing Zhang, et al. Construction of benzofuranone library via a metal-free,one- -pot intermolecular condensation, and their application as efficient estrogen receptor β modulators.Chemical Communications. 2019, 55, 14570. (共同- -作)
[3] Li Yuanyuan, Zhang Silong, Zhang Jing, et al. Exploring the PROTAC degron candidates: OBHSA withdifferent side chains as novel selective estrogen receptor degraders (SERDs). Eur J Med Chem 2019, 172,48-61. (第二作者)